Slender tufted | Broad tufted | P | |||
---|---|---|---|---|---|
Adapting (n = 5) | Bursting (n = 6) | Adapting (n = 4) | Regular spiking (n = 6) | ||
Electrophysiology | |||||
Ratio ISI-1/ISI-9 | 0.15 ± 0.03 | 0.09 ± 0.02 | 0.11 ± 0.01 | 0.21 ± 0.05 | 0.07 |
Ratio ISI-2/ISI-9 | 0.28 ± 0.06 | 0.14 ± 0.04 | 0.28 ± 0.03 | 0.51 ± 0.10 | <0.01 |
Ratio ISI-3/ISI-9 | 0.42 ± 0.07 | 0.21 ± 0.06 | 0.53 ± 0.04 | 0.77 ± 0.08 | <0.01 |
Increase in firing frequency (Hz/100 pA) | 6.1 ± 0.3 | 1.3 ± 0.2** | 8.0 ± 1.0 | 6.5 ± 0.8 | <0.01 |
Membrane potential (mV) | -67.0 ± 0.1 | -66.2 ± 1.0 | -71.5 ± 1.9 | -78.8 ± 0.8** | <0.01 |
Input resistance (MΩ) | 152 ± 24 | 138 ± 13 | 185 ± 9 | 143 ± 10 | 0.21 |
Rheobase (pA) | 110 ± 24 | 122 ± 11 | 115 ± 16 | 238 ± 11** | <0.01 |
Time constant (ms) | 32.0 ± 5.9 | 27.6 ± 1.3 | 27.1 ± 2.7 | 18.7 ± 0.5 | 0.04* |
Voltage sag (%) | 11.7 ± 3.2 | 11.7 ± 1.5 | 3.0 ± 1.4 | 0.2 ± 0.4 | <0.01 |
Morphology | |||||
Location in L3 (%) | 62 ± 14 | 49 ± 8 | 29 ± 6 | 21 ± 7 | 0.02* |
Field span apical dendrites (μm) | 214 ± 12 | 193 ± 20 | 312 ± 14 | 249 ± 10 | <0.01 |
Field span basal dendrites (μm) | 338 ± 56 | 276 ± 13 | 270 ± 19 | 252 ± 17 | 0.23 |
Total length apical dendrites (μm) | 1081 ± 89 | 1244 ± 119 | 2011 ± 146 | 2448 ± 265 | <0.01 |
Total length basal dendrites (μm) | 3733 ± 734 | 3123 ± 248 | 2609 ± 330 | 2901 ± 243 | 0.36 |
Soma (μm2) | 258 ± 32 | 193 ± 20 | 178 ± 14 | 181 ± 7 | 0.05* |
Number of apical branches | 7.4 ± 0.4 | 7.5 ± 0.6 | 13.8 ± 1.5 | 16.7 ± 2.1 | <0.01 |
Number of basal branches | 26.2 ± 3.0 | 24.0 ± 2.5 | 23.5 ± 3.2 | 25.3 ± 1.3 | 0.87 |
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Note: For clarity, the results of the post hoc comparison of groups is only given (values in bold followed with asterisks) when a cell type is different from all other cell types. *P < 0.05, **P < 0.01.